Mixed connective tissue disease as a cause of fever of origin to be determined

Abstract

The Fever of Origin to Be Determined, constitutes a real challenge for the doctor, since it can be caused and developed by multiple causes among which can be mentioned: infectious, neoplastic, vascular collagen, miscellaneous and idiopathic diseases. Causes associated with connective tissue disease account for 33% to 40% of cases. The objective of this report is to present a case of a woman, 28 years old, who after multiple studies, repeated income hospital and persistence of his fever, eight months later, symptoms compatible with lupus, polymyositis and scleroderma appear; so the diagnosis of Mixed Connective Tissue Disease was considered